Whether patients with nephritis can take clarithromycin mainly depends on the degree of renal function damage, if the patient’s renal function damage is mild, under the guidance of the doctor can take; if the patient has moderate to severe renal function damage need to be used with caution, at this time it is not recommended to take, to avoid aggravation of the condition. Clarithromycin is mainly applied to nasopharyngeal infections, such as tonsillitis, pharyngitis, paranasal sinusitis, etc.; lower respiratory tract infections, such as bronchitis, bacterial pneumonia, atypical pneumonia, etc.; skin infections, such as impetigo, erysipelas, folliculitis, boils and wound infections. It may occur oral odor, abdominal pain, diarrhea, nausea, vomiting and other gastrointestinal reactions, headache, transient elevation of serum aminotransferase, allergies and other adverse reactions. It is also contraindicated for allergy to macrolides, pregnant women, lactating women, people with severe hepatic impairment, water-electrolyte disorders, people taking terfenadine for treatment, and patients with certain heart diseases such as cardiac arrhythmia and heart failure. If patients with nephritis have infections, it is recommended to go to regular hospitals in time and standardize the treatment under the guidance of doctors.