Allergic rhinitis is an allergic disease that occurs in the nose. Paracetamol, or chlorpheniramine maleate, is an anti-allergic drug that is useful for allergic rhinitis, but it is rarely used because of its obvious drowsiness. Allergic rhinitis is a disease of allergic reaction of the nasal mucosa after contact with allergens, which can be manifested as itchy nose, watery nasal discharge, sneezing, nasal congestion and other symptoms. Allergic rhinitis treatment mainly uses glucocorticoid drugs, local nasal spray combined with anti-allergy drug treatment. Glucocorticoid nasal spray drugs are mometasone furoate, budesonide, fluticasone and so on. Anti-allergic drugs are commonly used second-generation antihistamines such as loratadine and cetirizine. Chlorpheniramine maleate is the first generation of H1 antihistamines, mainly used in anti-allergy treatment, but the main side effects can lead to produce drowsiness, thirst, polyuria and other adverse reactions, it is not recommended to have high altitude work, driving a car or ship, pregnant women and breastfeeding women to use. Due to its side effects, it is now rarely used in the treatment of allergic rhinitis. Allergic rhinitis is recommended to hospitals, follow the doctor’s instructions to standardize the use of medication.