Based on the pathological classification of lymphomas, the highly aggressive lymphomas are Lymphoblastoma and Burkitt’s Lymphoma. Lymphoblastomas are non-Hodgkin’s lymphomas and include both B-cell and T-cell sources. The former is mainly seen in children and presents with leukemia, usually with extensive involvement of the bone marrow, while the latter is most commonly seen in adolescents and presents with localized masses, most often involving the thymus. Burkitt’s lymphoma (BL) is also a non-Hodgkin’s lymphoma, which is associated with EBV infection. It is most common in children and adolescents. Endemic BL tends to involve the jawbone and presents as a large maxillofacial mass. Sporadic BL mostly involves the ileocecal region, manifesting as a huge mass in the abdominal cavity. Lymphoma needs to go to the regular hospital in time.