Positive H. pylori dpm190 indicates H. pylori infection, the specific severity depends on whether there are other concomitant diseases, and most of them can be converted to negative after active treatment. H. pylori infection is often associated with stomach pain and bloating, and most people also have bad breath. Moreover, studies have shown that H. pylori is associated with the development of gastritis, gastric ulcer and even gastric cancer. Therefore, the emergence of Helicobacter pylori dpm190 positive, it is recommended to further examination, such as gastroscopy, etc., to clarify whether there are other stomach diseases, at the same time against the Helicobacter pylori bacteria are often used in clinical quadruple therapy. Specifically a proton pump inhibitor such as omeprazole, a bismuth agent such as bismuth potassium citrate, two antibiotics such as amoxicillin, metronidazole and so on. The presence of Helicobacter pylori dpm190 positive, should be given great importance, timely medical treatment, and actively cooperate with the doctor’s treatment program, to promote the eradication of Helicobacter pylori, but also regular review and so on.