The most effective way to relieve liver pain does not exist. Liver pain may be caused by physiological factors, liver diseases, biliary tract diseases, etc. It can be relieved by adjusting lifestyle, medication and surgery. 1. Physiological factors: overwork, strenuous exercise and other reasons lead to increased load on the internal organs, increased blood transportation in the body causes pressure on the internal organs, and liver pain occurs. In daily life, we should keep enough sleep, avoid strenuous exercise, avoid eating stimulating food, can relieve liver pain. 2. Liver disease: viral hepatitis should be oral entecavir and other anti-viral treatment, liver abscess should use cefoperazone and other drugs for anti-infection treatment, if necessary, can also be used to drain pus puncture drainage. Patients with abnormal liver function can be treated with hepatoprotective and enzyme-lowering drugs, such as anti-inflammatory drugs such as compound glycyrrhizin tablets and detoxifying drugs such as injectable thiopronin, as well as painkillers such as diclofenac sodium extended-release tablets. If it is caused by tumor factor, surgical resection is preferred, and the surgical plan includes partial hepatectomy, segmental hepatectomy and so on. 3. Biliary tract diseases: If liver pain is caused by biliary tract diseases such as gallbladder stones and bile duct stones, it is recommended to have timely surgical treatment, such as cholecystectomy, choledochotomy and lithotripsy. Specific medications should be taken as prescribed by the doctor. If liver pain cannot be relieved in time, you should consult a doctor for a clear diagnosis and proper treatment under the doctor’s guidance.