The next day after drinking alcohol, spitting acid water and nausea, mostly considered acute erosive gastritis, reflux esophagitis, indigestion and so on, it is recommended to take rabeprazole and other acid inhibiting drugs, itopride and other gastric dynamics drugs and thioglycollate aluminum and other gastric mucosa protection drugs for treatment. 1. Acid-suppressing drugs: when patients drink alcohol leading to acute erosive gastritis, reflux esophagitis, etc., damage to the esophagus and gastric mucosa, spitting acid water, nausea, at this time to take acid-suppressing drugs to relieve spitting acid water, nausea and other discomforts, such as omeprazole, rabeprazole and so on. 2. Gastric power drugs: after drinking alcohol indigestion, resulting in gastrointestinal peristalsis is too slow, appropriate to take gastric power drugs, to promote gastrointestinal power such as Mosapride, Itopride, etc., so that the stomach food as soon as possible to digest, to relieve the symptoms of nausea. 3. Gastric mucosa protection drugs: drinking alcohol can lead to esophageal and gastric mucosal damage, causing acute erosive gastritis, reflux esophagitis, at this time, we should take appropriate gastric mucosa protection drugs to avoid inflammation, such as aluminum carbonate gel, magnesium aluminum carbonate and so on. In addition, patients should drink warm water, light diet, avoid spicy and stimulating food, consult a physician before using medication, not self-medication. If the symptoms are not relieved or aggravated, consult a doctor in time and follow the doctor’s instructions.