Waking up at 1:00 to 2:00 may be caused by physiological factors, environmental factors, psychological disorders, illnesses and so on. 1. Physiological factors: If you sleep too much during the day, you may not fall asleep easily at night or wake up early after falling asleep. 2. Environmental factors: If the patient lives in an environment with bright light, too noisy outdoors at night, or the temperature in the bedroom is too low or too high, it will easily cause the patient to wake up at 1:00 to 2:00 pm. 3. Psychological factors: If the patient encounters serious life events or excessive work pressure, it will lead to waking up at 1:00 to 2:00 pm. 4. Disease factors: If the patient has congestive heart failure, dementia, Parkinson’s disease, familial insomnia, perimenopausal syndrome, etc., it will wake up at 1:00 to 2:00 pm. If there is always a 1:00 to 2:00 wake up situation, it is recommended that patients go to the hospital in a timely manner, can be targeted treatment under the guidance of the doctor.