Vitamin A cream and fusidic acid cream have different ingredients and effects, and patients have different results after using them, so there is no such thing as which one is better. 1. Vitamin A acid cream is a kind of medicine that regulates skin keratinization, promotes the shedding of keratinocytes, and dissolves keratinous plugs. It is used for the treatment of acne vulgaris, flat warts, mucous membrane leukoplakia, hairy erythema, follicular keratosis, and so on. Adverse effects of the drug are that its use may cause symptoms of skin irritation, such as burning sensation, erythema and flaking. Contraindications to the use of the drug are: contraindicated in women during the first 3 months of pregnancy, lactating women; contraindicated in people who are allergic to any of the components of the product; contraindicated in the eyes. The drug should not be used in skin folds; eczema, sunburn, acute and subacute dermatitis, rosacea patients should not use the drug. 2. Fusidic acid cream is a dermatologic antimicrobial agent mainly used for skin infections caused by gram-positive cocci, such as impetigo, boils, onychomycosis, traumatic infections, bearded sores, tinea cruris, folliculitis, acne vulgaris and so on. Adverse effects of the drug are contact dermatitis, rash, eczema, erythema, maculopapular rash, itching, and skin allergic reactions may occur after use. Contraindications to the use of the drug are: it is contraindicated in case of hypersensitivity to any of the components of the product. The drug has an irritating effect on the conjunctiva of the eye, try to avoid using it around the eyes. Caution is advised for pregnant and lactating women. Retinoic acid cream or fusidic acid cream should be used under professional medical supervision.