Men can delay the drug is mostly for premature ejaculation drugs, including local drugs such as lidocaine – proparacaine cream, 5 – hydroxytryptamine reabsorption inhibitors such as dapoxetine, tricyclic antidepressants such as chlorpromazine. 1. Topical drugs: such as lidocaine-proparacaine cream, the use of this type of local anesthetic effect of the ointment can reduce the sensitivity of the head of the penis, which is conducive to prolonging the ejaculation latency of patients with premature ejaculation. 2.5-hydroxytryptamine reabsorption inhibitors: including dapoxetine, sertraline and other drugs. The treatment of premature ejaculation has a certain therapeutic effect. 3. Tricyclic antidepressants: such as chlorpromazine, is the first antidepressant used to treat premature ejaculation, but the incidence of adverse reactions is high. The above drugs should be applied under the guidance of a doctor.