Eb virus with ganciclovir 2 days and still have a fever, it may be a natural process of the virus, or it may be complicated by infectious mononucleosis, which requires further examination. The vast majority of people infected with EBV are latently infected, or only have mild cold symptoms, such as fever and sore throat for three to five days after which they usually clear up on their own, and can appear to have Eb virus with ganciclovir 2 days still have fever. However, some patients, especially adolescents and adults will develop infectious mononucleosis. This is characterized by fever, sore throat, hepatosplenomegaly, enlarged lymph nodes, and an increase in the proportion of peripheral lymphocytes and heterogeneous lymphocytes. At this time, high fever persists, and there can be a fever even after 2 days of ganciclovir for EBV. Therefore, it is necessary to complete the examination, first of all, should test the blood routine, at the same time, test the count of heterotypic lymphocytes, liver and kidney function, if necessary, can be carried out PCR detection of EBV DNA quantification, can be determined by abdominal ultrasound liver and spleen enlargement, and so on. Infectious mononucleosis is usually treated with symptomatic supportive therapy, combined with antiviral drugs such as ganciclovir, and the prognosis for EBV infection and mononucleosis without complications is good.