The difference between picosecond laser and photorejuvenation lies in the different skin problems and treatment effects. 1. Different skin problems: Picosecond laser can be used for the treatment of enlarged pores or pigment-damaged skin diseases, while photorejuvenation can be used for pigmented and vascular diseases and facial rejuvenation. 2. Different therapeutic effects: picosecond laser by using picosecond light pulse positioning is more precise, divided into two bands, namely, 532nm, 1064nm, the treatment may be short-term scabs, in the rejuvenation of whitening at the same time also does not leave scars, no bleeding. Photorejuvenation can smooth fine wrinkles, shrink large pores, improve the symptoms of skin roughness and play a certain whitening effect, also has a therapeutic effect on capillary dilatation. Everyone’s skin type and disease conditions are different, under the guidance of a professional doctor according to their own situation, choose the right way to improve the skin.