High GGT glutamyl transpeptidase may be caused by drugs, alcohol consumption, liver disease, etc. It can be treated by alcohol cessation, drugs such as entecavir, and surgery. 1. Drugs: some drugs such as streptokinase, phenobarbital, etc. can cause GGT elevation, at this time, you need to stop using drugs to make GGT return to normal. 2. caused by drinking: long-term drinkers have certain damage to the liver, resulting in GGT elevation, so you need to quit drinking. 3. caused by liver disease: in the active stage of acute hepatitis, chronic hepatitis or cirrhosis, part of the liver cells are hypercompensated and GGT secretion is increased, at this time, it is necessary to treat the liver disease according to the etiology. Such as chronic viral hepatitis need to be entecavir and other antiviral drugs, licorice extract and other enzyme-lowering drugs. 4. Due to biliary tract disease: biliary tract obstruction blocks the discharge of GGT, and GGT flows back into the blood, resulting in high GGT. At this time, it is also necessary to treat biliary tract diseases according to the cause. For example, bile duct stones can be removed surgically. There are many other causes of high GGT, if the GGT test result is abnormal, it is recommended to consult a doctor in time, with the help of the doctor to clarify the cause of the disease, and carry out targeted treatment or therapy.