The life expectancy of patients with locally advanced esophageal cancer does not have a relatively accurate value. Generally speaking, the survival time is different according to the sensitivity of treatment, malignancy of esophageal cancer, and physical condition of patients. Locally advanced esophageal cancer generally refers to patients with stage III in TNM staging, and the 5-year survival rate is commonly used to reflect the survival rate of patients, and the 5-year survival rate of patients with stage III esophageal cancer is around 15% to 20%, which indicates that the survival time of the majority of patients is less than 5 years. Generally speaking, for patients with locally advanced esophageal cancer, the more sensitive they are to the treatment, or the less malignant the cancer cells are, or the better their physical condition is, the survival time of the patients will be prolonged.