The use of cephalosporins in patients with pneumonia can generally be discontinued after the fever has subsided for 2 to 3 days and the main respiratory symptoms have improved significantly, and usually patients with mild to moderate pneumonia can be anti-inflammatory with 5 to 7 days of use. Severe cases and patients with extrapulmonary complications can be appropriately prolonged. Staphylococcus aureus, Pseudomonas aeruginosa, anaerobes and other bacteria are prone to cause necrosis of lung tissue, the course of treatment can be extended to 14 to 21 days. The use of cephalosporins may trigger allergic reactions, common rashes, itching, anaphylaxis and so on. Prolonged and massive application may lead to antibiotic-associated diarrhea and secondary infections. Cephalosporins may trigger cross-allergic reactions, so they are contraindicated for those who are allergic to cephalosporins, have a history of penicillin anaphylaxis or immediate reaction. Alcohol consumption is prohibited after the use of the drug, as it can provoke a disulfiram-like reaction. The patient’s medication regimen and course of treatment should be carried out under the guidance of a professional physician, do not stop the medication without authorization.