Generally the endocrine treatment time after radical prostatectomy for prostate cancer takes about 18 months, but there are individual differences. Prostate cancer is a common malignant tumor in elderly men, which can be clearly diagnosed through physical examination and prostate puncture biopsy, etc. Radical prostatectomy is the most effective way of treating prostate cancer according to doctor’s prescription, and after surgery, according to the condition of the patient, it is necessary to assist endocrine therapy, which can effectively control the growth and spread of residual tumors, and it usually takes about 18 months of treatment, but there are also differences in the treatment according to the individual’s condition. After surgery, patients should pay attention to proper rest, increase nutrition to promote physical recovery, and follow the doctor’s instructions for regular checkups. Due to the strong hormone dependence of prostate cancer, endocrine therapy can treat residual lesions at the margins of the incision, residual positive lymph nodes, as well as small metastatic lesions after surgery. If the patient is not feeling well, he should consult the doctor in time for examination and early treatment.