The nose due to cold and flu can be sprayed mometasone furoate nasal spray, seroquelizine hydrochloride nasal spray, hydroxymetazoline hydrochloride spray and other drugs. 1. Mometasone furoate nasal spray: it belongs to glucocorticoid nasal spray, which can inhibit the release of inflammatory factors and improve the symptoms such as sneezing, runny nose, and nose not working. Adverse reactions such as headache, nosebleed, pharyngitis, nasal ulcers may occur during use. It is contraindicated for those who are allergic to the ingredients of this product. 2. Seroquel hydrochloride nasal spray: it belongs to nasal decongestant drugs, which can reduce the congestion and edema of nasal mucosa, and can effectively improve nasal ventilation. Over-frequent use of drugs can easily lead to rebound nasal congestion, and prolonged use can lead to drug rhinitis. Atrophic rhinitis, dry rhinitis, hypertension, coronary heart disease, hyperthyroidism, diabetes mellitus, closed-angle glaucoma, women in pregnancy, etc. are prohibited. 3. Hydroxymetazoline Hydrochloride Spray: It is a nasal decongestant, which can clear the nasal passages and improve nasal ventilation. Too frequent use of the drug is likely to cause rebound nasal congestion, long-term use of the drug can lead to rhinitis. It is contraindicated in atrophic rhinitis and nasal dryness, in pregnant women and children under 2 years of age, and in patients receiving monoamine oxidase inhibitors (e.g. Pagylin). Nasal congestion symptoms can also be caused by other diseases, if the nasal congestion symptoms are not relieved or aggravated, you should promptly go to the hospital for consultation, to identify the cause of the problem and then give targeted treatment.