Long-term use of Glutathione can lead to an increased incidence of adverse reactions, and it is recommended that the drug be used under the guidance of a physician according to the condition. Glutamine is commonly used in neurosis, premenstrual tension syndrome, menopausal syndrome, and can regulate autonomic dysfunction and endocrine balance disorders. Its adverse reactions may include fatigue, nausea and vomiting, stomach upset, skin rash, breast swelling and pain, increased oil secretion, weight gain, hair loss, etc. All of the above adverse reactions can disappear after stopping the drug. If symptoms do not resolve after 1 week of use, patients should consult their physician to consider changing the drug. If the symptoms improve, the drug can be discontinued, avoid prolonged use of the drug, long-term use will lead to an increased incidence of adverse reactions. Patients with a history of gastric and duodenal ulcers should use this drug with caution to avoid aggravation of the condition.