The chin long closed mouth acne in terms of medication include the following: 1, oral medication: you can choose isotretinoin soft capsule or vitamin E capsule, this drug has certain side effects on the body, can cause liver function, lipid changes, but also can cause the newborn teratogenic, so during the period of taking regular laboratory tests of liver function, lipid. After taking the drug, stop using it for more than six months to achieve the purpose of contraception, so as to avoid the possibility of teratogenic fetuses. 2, topical drugs: you can choose to apply vitamin E ointment, vitamin A ointment or tazarotene gel, can play the purpose of anti follicular mouth keratinization, during the treatment period need to avoid eating sweets and alcoholic beverages.