Acne may go away on its own without squeezing. Acne is an inflammatory disease of the sebaceous glands and is associated with endocrine, bacterial infection, genetic factors, and poor skin care practices, and is most common in adolescents. However, if the acne is related to a disease, it is less likely to heal on its own. It is necessary to correct the problem and apply medication or other treatments to improve the symptoms. When acne occurs, medications can be applied according to the cause of the disease, such as retinoids, antibiotics, glucocorticoids, etc. Photodynamic therapy or laser treatment is also available. In addition, it is not recommended to squeeze the acne by hand after it occurs. The hands can carry bacteria, and when you squeeze the acne with your hands, the bacteria on your hands may enter the skin with the opening of the acne and increase the chance of skin infection, especially for acne in the perioral area, and you should not squeeze it with your hands to avoid causing inflammation resulting in upstream infection. During acne treatment, in addition to not squeezing with your hands, you should also pay attention to keeping your skin clean, avoid scratching, choose a light diet, avoid spicy food stimulation, avoid staying up late, maintain regular rest and rest, keep your mood relaxed, and strictly apply medication as prescribed by your doctor, do not blindly believe in prescriptions to avoid aggravating discomfort or causing unnecessary damage.