The treatment includes the following aspects: 1, fruit acid treatment, so the treatment area of such patients is too large, rely solely on retinoids, easy to cause acne stimulation red, dry, and even peeling phenomenon, the skin can not tolerate, after the application of drugs also need to avoid light, the treatment is more cumbersome, the current clinical advice to use fruit acid for comprehensive treatment, the effect is better; 2, if the conditions do not allow, can be taken orally to improve the keratinization of drugs, such as vitamin ester capsules, vitamin A acid pills, etc., but also with anti-androgen drugs, internal and external comprehensive conditioning can achieve better results.