Goserelin is mainly indicated for the treatment of prostate cancer, breast cancer, and endometriosis. It can cause side effects in both men and women, including decreased libido, flushing, increased sweating, acne, mild bruising at the injection site, mood changes such as depression, abnormal sensation, blood pressure, skin rash, and hair loss, decreased bone density, and weight gain, which can be manifested as hypotension or hypertension. These reactions are temporary and recover at the end of treatment, and rarely require discontinuation of treatment. In addition, men are prone to erectile dysfunction and breast development, as well as tenderness, bone pain, and elevated blood glucose, etc. This bone pain is temporarily aggravated and should be treated symptomatically. For women it may cause vulvar and vaginal dryness, as well as vaginal bleeding, breast enlargement, ovarian cysts, etc.. Therefore, it is important to pay attention to the observation during the medication period, and any abnormal performance should be promptly consulted.