The precautions in the first trimester of pregnancy include reasonable rest, strengthening diet and nutrition, and reasonable supplementation of folic acid.1. Reasonable rest: usually pay more attention to rest, avoid exertion, especially to avoid staying up all night, and also pay attention to emotional regulation, relaxation, and avoiding excessive fluctuations in mood.2. Strengthening diet and nutrition: usually pay attention to a balanced diet and nutrition, do not picky, do not favorites, and moderate intake of foods containing high-quality proteins and vitamins, such as eggs, milk, fish, shrimp, apples, bananas, etc..3. Foods, such as eggs, milk, fish and shrimp, apples, bananas, etc. 3. Reasonable supplementation of folic acid: should be instructed by the doctor to take folic acid drugs, can enhance the immunity of pregnant women, to prevent fetal malformation. During pregnancy, women should pay attention to regular obstetric examination, and should consult the doctor in time when abnormalities are found, so that reasonable treatment can be carried out under the doctor’s guidance.