When patients with coagulation disorders bleed, they can usually be treated with sedation of coagulation factors, antifibrinolytic agents, surgery and physical therapy. 1. Coagulation factor supplementation, such as transfusion of cold precipitated or fresh plasma, is the mainstay of treatment for coagulation disorders, which can significantly increase the body’s hemostatic level. 2. Antifibrinolytic agents can be used for treatment, which can protect the blood clot that has formed from being dissolved, and are usually used for bleeding from oral wounds or after tooth extraction. 3. If the bleeding is very severe, then surgical suturing is also required. 4. If the patient is localized deep tissue hematoma or joint bleeding, it is also necessary to try to bed rest, the affected limbs appropriate elevation, supplemented by ice packs cold compresses, can also play a certain role in hemostasis. Specific drugs should be used under the guidance of a physician.