Pregnancy When a patient with polycystic ovary syndrome gets pregnant 1. I have been taking Metformin, do I need to continue taking it now that I am pregnant? Is this medication safe for pregnant women and fetuses? It is up to the doctor to decide if the medication needs to be continued based on the condition. Metformin is a class B drug in the classification of medication in pregnancy. Our latest Expert Consensus on Clinical Application of Metformin shows that oral metformin in early pregnancy does not increase the risk of fetal malformation and neonatal complications, and has advantages in controlling maternal weight and improving insulin resistance. Metformin can also be used to prevent gestational diabetes in the pre-gestational period. 2. I have had 3 spontaneous miscarriages and was found to have polycystic ovary syndrome, why does this disease cause me to have repeated miscarriages? According to statistics, the incidence of spontaneous miscarriage after pregnancy in patients with polycystic ovary syndrome is more than 3 times higher than that in women with normal pregnancy. Patients with polycystic ovary syndrome have endocrine metabolic disorders, inflammation and immune abnormalities that adversely affect the endometrial tolerance, just like the planting ground is not fertile, the seeds cannot take root and grow well even after planting. Thus, even if the embryo is successfully planted, the risk of developing a series of pregnancy complications and complications such as miscarriage, gestational diabetes, gestational hypertensive disorders and preterm delivery increases due to the further intensification of insulin resistance, in synergy with obesity and abnormal inflammatory immune response. 3.How to prevent miscarriage in patients with polycystic ovary syndrome? It is recommended that you should take reasonable interventions and standardized treatment under the guidance of doctors, such as oral short-acting combined contraceptive pills, oral insulin sensitizers, establishing a good lifestyle, insisting on appropriate exercise, etc.; pre-conception consultation and examination should be started three to six months before the next pregnancy, and the corresponding individualized treatment plan should be taken under the guidance of doctors after pregnancy, and reasonable weight control during pregnancy, etc., which can improve the adverse pregnancy outcome to a certain extent. The results can be improved to some extent. 4.What is the difference between maternity checkups for pregnant women with polycystic ovary syndrome and ordinary people? The prenatal checkups for mothers with polycystic ovary syndrome are not very different from those for normal mothers of childbearing age. However, mothers with polycystic ovary syndrome are more prone to pregnancy complications such as gestational hypertension and gestational diabetes during pregnancy, and because pregnancy is more difficult for women with polycystic ovary syndrome than for ordinary women, they can be classified as “relatively high-risk pregnancy”. Therefore, it is recommended that patients with polycystic ovary syndrome can take the initiative to communicate with their maternity doctors and inform them of their medical history to increase the frequency of prenatal checkups as appropriate. However, it does not mean that mothers-to-be with polycystic ovary syndrome need to be overly nervous. When a mother with polycystic ovary syndrome becomes a mother, will my child get this disease in the future if I am diagnosed with polycystic? Like chronic diseases such as hypertension, diabetes and rheumatism, polycystic ovary syndrome is a polygenic disease. These diseases have certain genetic factors, and the next generation is more likely to develop the disease than other people, but their development is triggered by certain environmental conditions. In other words, the probability of your daughter getting this disease is higher than the average child, and whether or not the disease develops depends largely on the influence of environmental factors later in life. What can a mother with polycystic ovary syndrome do to prevent her child from getting the disease? First of all, prepare fully before pregnancy, adjust your endocrine and metabolic status well, listen to the doctor’s guidance, take reasonable medication, exercise properly, and have regular checkups, so that you can prepare for pregnancy in a healthy state; secondly, manage reasonably during pregnancy, under the doctor’s guidance, manage your weight during pregnancy, have regular maternity checkups, and monitor blood sugar, blood pressure and other indicators regularly, so that your baby grows in a healthy environment before birth and has a healthy body at birth. Finally, after the birth of your child, you and your child should work together to create a healthy and good life style, including eating habits, exercise habits and living habits. Even if you are a mother with polycystic ovary syndrome, you can try to minimize or even prevent the occurrence of polycystic ovary syndrome in the next generation by establishing a good lifestyle and environment. 3. Can a patient with polycystic ovary syndrome leave the disease alone after having a baby? Polycystic ovary syndrome is called a syndrome precisely because of its complex and diverse manifestations, which can affect from adolescence, to fertility, and all the way to old age. The effects during the reproductive years are often infertility and menstrual disorders. After solving the problem of fertility, we need to focus on metabolic problems and menstrual problems, and if we ignore it after childbirth, the risk of diabetes, cardiovascular disease, and even endometrial cancer will remain higher than in the general population. Therefore, polycystic ovary syndrome is a chronic disease that needs our long-term attention and long-term management. 4. My daughter is studying and has irregular menstruation, does she have polycystic ovary syndrome? Not all irregular periods are due to polycystic ovary syndrome. Irregular periods, especially in adolescence, can be caused by many reasons. gradually become regular. In addition, many reasons inside and outside the body, such as stressful studies, mental tension, poor nutrition, excessive exercise, eating disorders, low weight and other medication effects, may lead to irregular periods. Patients with polycystic ovary syndrome can also have irregular periods, but to determine if they really have the disease, they must see a doctor at a regular hospital and be sure after an examination.