Immunohistochemistry results of breast cancer mainly include ER, PR, HER-2 and KI-67. ER and PR mean estrogen receptor and progesterone receptor respectively.
When the test report to show that: ER positive or PR positive, and greater than a certain value, it means that the patient’s cancer cells on the surface of the existence of these two receptors, at this time the patient can be treated with endocrine drugs (tamoxifen, letrozole, etc.).
HER-2 represents a growth factor receptor associated with the development of breast cancer and often represents a poor prognosis; a positive HER-2 indicates that the patient can be treated with targeted agents such as trastuzumab, patuximab, etc. If all three of the above are negative, the patient can be treated with endocrine agents (tamoxifen, letrozole, etc.).
If all three of the above are negative, it is called triple-negative breast cancer, which is one of the poorer prognoses of all breast cancers and can only be treated with conventional chemotherapy drugs such as docetaxel and paclitaxel.
KI-67 represents the proliferation ability of tumor cells, the higher the value, the more active the proliferation of tumor cells, there is no special medication, but will guide the clinician to master the cycle and program of medication.
Please strictly follow the doctor’s instructions for drug treatment, and do not use drugs on your own.