Metformin extended-release tablets are suitable for patients with type 2 diabetes mellitus who cannot obtain good control with diet and exercise therapy alone, they are not weight-loss drugs and are not recommended for patients who want to lose weight. Metformin extended-release tablets are insulin sensitizers, which can inhibit intestinal glucose absorption, hepatic gluconeogenesis and output, increase the uptake and utilization of glucose in tissues, improve insulin sensitivity, and thus achieve the effect of lowering glucose. Adverse reactions such as nausea, vomiting, diarrhea, abdominal pain, dyspepsia, flushing, chills, chest discomfort, malaise, fatigue, etc. may occur in some patients after taking it. When adverse reactions occur, patients are advised to stop taking the drug and seek medical attention. This product is taken during or after meals, chewing and oral intake is prohibited, and should be swallowed whole. Nursing women should be cautious, pregnant women, allergic to the product, type 2 diabetes mellitus with ketoacidosis, hepatic and renal insufficiency, heart failure, acute myocardial infarction, clinical hypotension and hypoxia, previous history of lactic acidosis and so on are prohibited, and allergic reactions such as skin rashes should be discontinued. Patients who want to use metformin extended-release tablets for weight loss are advised to go to a regular hospital, consult a professional doctor, cooperate with the doctor to complete the relevant examinations, and avoid blind use of medication.