Side effects of acetaminophen are usually seen as skin reactions and liver and kidney impairment. Acetaminophen has antipyretic and analgesic effects by inhibiting prostaglandin synthesis and is used for the common cold or fever caused by it. It is also used to relieve mild to moderate pain such as headaches, joint pain, migraines, muscle pain, neuralgia, and menstrual cramps. Its common side effects are seen in skin reactions including reddening of the skin, blisters, and rashes, while uncommon side effects include urticaria, drug fever, and granulocytopenia, and prolonged and heavy use of the drug can lead to abnormalities in liver and kidney function. Therefore, the dosage of this product should be applied in strict accordance with the instructions; severe hepatic and renal insufficiency is prohibited, long-term use of the drug should be checked regularly for liver biochemical indicators, allergic individuals should be cautious, and those who are allergic to this product are prohibited. Try to avoid the combined use of drugs containing acetaminophen or other antipyretic and analgesic drugs, in order to avoid overdose or lead to toxic synergistic effects. Drugs should be used under the guidance of a specialized physician or pharmacist.