When lactate dehydrogenase is 289U/L, it is not normal, it is mildly elevated and generally has no clinical significance; if it is elevated in large quantities it is generally associated with cardiac disease, liver disease, malignant tumors and so on. Lactate dehydrogenase normal reference value range of 120 ~ 250U / L, so lactate dehydrogenase for 289U / L mildly elevated, lactate dehydrogenase in the human body to the cardiac muscle, skeletal muscle and kidneys in the most abundant, myocardial infarction and other cardiac diseases can be caused by lactate dehydrogenase significantly elevated. Acute viral hepatitis, cirrhosis and other liver diseases can also cause lactate dehydrogenase elevation. In addition, malignant lymphoma, lung cancer, colon cancer and other malignant tumors can cause elevated lactate dehydrogenase; anemia, pulmonary infarction, skeletal muscle injury and so on can also cause high lactate dehydrogenase. When lactate dehydrogenase is high, the cause should be clarified under the guidance of doctor for active treatment.