The treatment of pyelonephritis mainly consists of anti-infective treatment and general treatment such as drinking more water and urinating regularly, in addition, chronic pyelonephritis needs nephrotic integration treatment. Pyelonephritis is an infectious disease, usually caused by bacterial or other pathogen infection, which is divided into acute pyelonephritis and chronic pyelonephritis. 1. Anti-infection treatment: The treatment program for acute pyelonephritis and chronic pyelonephritis is mainly to apply sensitive antibiotics for anti-infection treatment, and the more commonly used ones are cephalosporins such as cefuroxime or quinolones such as ofloxacin. 2. General treatment: in the acute stage of pyelonephritis, we should pay attention to rest, drink a lot of water and urinate frequently. Recurrent patients should actively search for the cause of the disease and remove the triggering factors in time. 3. Renal integrated treatment: Chronic pyelonephritis non-exacerbation also needs renal integrated treatment, such as controlling blood pressure, lowering creatinine, protecting renal function and so on. When pyelonephritis occurs, it is recommended to consult the doctor in time and treat it actively under the guidance of the physician.