Difficulty in urination in the elderly may be caused by prostate enlargement, urethral stenosis, bladder stones, neurogenic bladder, etc. The main treatments include medication, lithotripsy and surgery. 1. Prostatic hyperplasia: For urination difficulties caused by prostatic hyperplasia, drugs such as tamsulosin and finasteride can be applied for treatment, and surgical treatment such as transurethral resection of prostate can be considered in serious cases. 2. Urethral stenosis: For urethral stenosis that causes difficulty in urination, after diagnosis, surgical treatment, such as urethral dilatation surgery, is usually performed. 3. Bladder stones: the presence of bladder stones can also cause difficulty in urination, which may be accompanied by painful urination. When the stones are large and cannot be removed on their own, transurethral cystoscopic lithotripsy may be considered. 4. Neurogenic bladder: it may be related to diabetes, after diagnosis, it can be treated with hypoglycemic and nutritive drugs, such as metformin and methylcobalamin, etc., and cystostomy can be performed if drug treatment is not effective. In the course of treatment, elderly patients must follow the doctor’s instructions, safe and reasonable use of drugs, do not self-medication.