Vocal fold closure insufficiency, according to the degree of closure insufficiency can be divided into mild, moderate and severe, can be manifested as hoarseness, vocal leakage, can not be normal voice and other symptoms. 1. Mild occlusal insufficiency: Inflammation such as congestion and edema on the surface of the vocal folds leads to occlusal insufficiency of the vocal folds, which is manifested as mild hoarseness. 2. Moderate closure insufficiency: long-term or chronic inflammation on the surface of the vocal folds leads to nodules, polyps or malignant tumors on the vocal folds, resulting in bilateral closure insufficiency of the vocal folds, which can be manifested as leakage of air in the voice, and the voice shows obvious hoarseness. 3. Severe closure insufficiency: paralysis of the laryngeal reentry nerve causes one side of the vocal folds to be normal and the other side to be paralyzed, or bilateral paralysis of the vocal folds, which may lead to severe closure insufficiency of the vocal folds, manifesting as the inability to pronounce sound normally and severe air leakage. Symptoms of vocal fold closure insufficiency should be timely medical treatment, under the guidance of the doctor to clarify the diagnosis, targeted treatment.