The face suddenly grows a small grain feel very rough consider and flat warts, acne, peripheral keratosis, etc., the treatment should be based on the cause of the choice of general treatment, medication, physical therapy and other ways of treatment. 1. flat warts: this disease is caused by human papillomavirus (HPV) infection, most of the manifestations of skin color or light brown flat papules, can be treated by laser and other physical therapy. 2. Acne: If the patient’s facial oil secretion is high and the acne bacteria multiply, there will be pimples, pustules and other polymorphic lesions. At this time, the patient can follow the doctor’s instructions to use retinoic acid ointment, adapalene gel, azelaic acid and other topical application, and when the main manifestation of pimples, it is possible to combine with fruit acid resurfacing and other treatments. 3. perifollicular keratosis: this disease is a chronic follicular keratosis dermatosis, patients are mostly manifested as follicular keratin plugs, keratinized pimples consistent with the pores, at this time you can follow the doctor’s instructions to use urea ointment, salicylic acid ointment and other keratolytic agents to soften or dissolve keratin For the face suddenly long small grains feel very rough patients, it is recommended to the regular hospital dermatology consultation, clear causes under the guidance of the doctor active treatment.