High monocytes cannot determine whether it is bacterial or viral, the identification of bacteria and viruses is most important to do the culture of pathogens, and the increase can be seen mainly in certain blood diseases. Infants, children, monocytes will be physiological slightly increased, but in other cases the increase is a pathologic increase, mainly in certain infections such as malaria, active tuberculosis, the recovery phase of acute infections, subacute infective endocarditis, etc. can be significantly increased. It is also seen in certain blood diseases such as granulocyte deficiency recovery, chronic granulocytic leukemia, monocytic leukemia and so on. When the monocyte increase should consult the doctor in time, the doctor based on clinical manifestations, physical examination and other comprehensive analysis to make a judgment, improve the relevant examination such as bone marrow aspiration, etc., to clarify the cause of the disease, targeted treatment to improve the quality of life.