Blisters on the soles of the feet and walking pain, need to be cleaned and disinfected locally, appropriate bandage, and anti-infective treatment, if necessary, also need to puncture and draw fluids. When walking with pain from blisters on the soles of the feet, first of all, rest more, minimize foot friction. If the blister is relatively small, direct outer layer disinfection, no need to draw fluid. After sterilization, local erythromycin ointment can be applied to prevent infection. You can use sterile gauze to bandage the localization and reduce the pain. If the blisters are large and it takes a long time for them to absorb on their own, it is recommended to go to the hospital as soon as possible. After local disinfection by a professional doctor, the blisters will be punctured, the liquid inside the blisters will be discharged, antibiotics will be applied locally to fight infection, and finally a local bandage will be applied to the blisters, and the dressing will be changed every day at regular intervals. Do not tear off the skin of the blister on your own, just wait for the scab to form and the skin to grow back and slowly fall off. During the recovery period, you should pay attention to a light diet and eat less spicy and stimulating food.