Clinically, young people’s knee rheumatic pain may be related to gout, rheumatoid arthritis, ankylosing spondylitis and other diseases, the available non-steroidal anti-inflammatory drugs, glucocorticosteroids and other drugs. 1. Non-steroidal anti-inflammatory drugs: clinically commonly used ibuprofen and other non-steroidal anti-inflammatory drugs to relieve rheumatic joint swelling and pain, the general efficacy is obvious. Renal insufficiency, asthma, active bleeding, etc. are prohibited, and the most common adverse reaction is peptic ulcer. 2. Glucocorticosteroids: for non-steroidal anti-inflammatory drug efficacy is not good or there are contraindications or the need to stop the adverse effects of the drug, can be under the guidance of the doctor to choose oral or joint cavity injection glucocorticosteroids, such as prednisone, betamethasone, etc., should be individualized treatment. Rheumatism caused by knee pain need to pay attention to warmth, rest, and active treatment of rheumatism, you can go to the regular hospital rheumatology and immunology department and other related departments for detailed consultation, follow the doctor’s instructions for standardized treatment, do not self-medication.