Is allopurinol the drug of choice for lowering uric acid?



Allopurinol is one of the first choice drugs for lowering uric acid, and it is recommended to use the drug under the guidance of a doctor, and other first-line drugs include febuxostat and benzbromarone.

Allopurinol is a xanthine oxidase inhibitor, which can inhibit uric acid synthesis, and is one of the first-line drugs for hyperuricemia, as well as for the treatment of gout and uric acid nephropathy.

Allopurinol is contraindicated in people who are allergic to this drug, have severe hepatic or renal insufficiency and markedly low blood counts. Gastrointestinal reactions such as diarrhea, nausea, vomiting, skin rash, leukopenia and other adverse reactions may occur during use. If significant discomfort occurs, seek immediate medical attention.

Note that it should be applied only after the acute inflammation of gout has disappeared. Drink plenty of water during the medication and make the urine neutral or alkaline to facilitate the excretion of uric acid. Begin to use the drug in small doses, should not be taken with iron, and regularly check the blood and liver and kidney functions during the use of the drug.

In addition to allopurinol, the first-line drugs for lowering uric acid include febuxostat and benzbromarone.

The above drugs are recommended to be used under the guidance of a doctor to avoid adverse reactions.