The chance of recurrence after HPV16 conization is relatively small, but there is a possibility of recurrence. HPV is human papillomavirus, and HPV16 is usually referred to as human papillomavirus type 16, which is a high-risk type of virus that has a relatively large impact on the body and may cause cervical cancer. After HPV16 conization does not mean complete cure, there may still be a small amount of residual virus in the body, which has a relatively small impact on the body, and it may still be active again in the following daily life if the resistance is weak or other factors affect it, resulting in a resurgence of the positive situation. Although the chances of recurrence after HPV16 conization are relatively small, attention should be paid to regular gynecological consultation and review as prescribed by the doctor, pay attention to personal hygiene and care, appropriate exercise, improve immunity, and minimize the possibility of recurrence.