In most cases, there is no reaction to the use of metronidazole suppositories inserted into the vagina. However, if an individual is allergic to metronidazole, it may cause local allergic reactions, which may lead to localized itching of the vagina or redness and swelling of the vulvar mucosa, it is recommended that if this phenomenon occurs, the drug should be stopped immediately, and other drugs should be used for the treatment, and after the individual use of metronidazole suppositories, in the clinic due to the relatively more serious inflammation, local burning sensation may occur or localized pain may occur. The situation. The vast majority of continue to use the drug, this situation will gradually disappear, and also recommended that if the clinical treatment with metronidazole, often used for trichomonas vaginitis, miscellaneous bacterial infections, bacterial vaginosis, you can use metronidazole suppositories to give the treatment, and it is recommended that must be in the guidance of the doctor before using the drug.