Untreated gallbladder stones may induce acute cholecystitis, acute pancreatitis, increase the risk of gallbladder cancer and other complications. 1. Acute cholecystitis: gallbladder stones directly damage the mucous membrane of the gallbladder at the site of pressure, coupled with gallbladder stones lead to obstruction of the gallbladder ducts resulting in bile stagnation, bile is a good culture medium for bacteria, pathogenic bacteria retrograde through the bile duct into the gallbladder, through the damaged mucous membrane of the gallbladder invasion of the gallbladder, resulting in cholecystitis occurs. 2. Acute pancreatitis: Smaller gallbladder stones can enter into the common bile duct and pass through the sphincter of Oddi, which can cause injuries or become embedded in the jugular abdomen, resulting in obstruction of the pancreatic duct and elevation of the intra-pancreatic pressure, which can lead to the occurrence of acute pancreatitis. 3. Gallbladder cancer: 70% of gallbladder cancer patients are related to gallstones, and gallbladder stones cause the gallbladder to be in the state of long-term chronic inflammatory stimulation. It is suggested that patients with gallbladder stones should go to the hospital in time, and under the guidance of the doctor, carry out regular treatment to minimize the complications caused by gallbladder stones as much as possible.