Antidepressant drugs, including SSRIs (5-hydroxytryptamine reuptake inhibitors) such as fluoxetine, SNRIs (norepinephrine reuptake inhibitors) such as venlafaxine, NASSAs (serotonergic antidepressants) such as mirtazapine, NDRIs (norepinephrine and dopamine reuptake inhibitors) such as bupropion. 1. SSRIs: common drugs include fluoxetine, sertraline, etc. In the acute phase of treatment, this drug is more effective than placebo, and there is no significant difference in the overall efficacy of different SSRIs. 2. SNRIs: common drugs include venlafaxine, duloxetine, the efficacy of the drug is dose-related, for the treatment of patients with depression combined with diabetes mellitus or peripheral neuralgia is more advantageous than SSRIs. 3.NaSSAs: common drugs include mirtazapine, the drug has significant improvement on symptoms such as decreased appetite and sleep disorders in patients with depression, and can cause less sexual dysfunction. 4. NDRIs: common drugs including bupropion, the drug for fatigue, sleepiness improvement is more significant, and less impact on weight gain, and can even reduce weight, applicable to overweight or obese patients. If you need to take antidepressants in daily life, it is recommended to take them under the guidance of doctors in regular hospitals to avoid unauthorized use of medication.