Saxagliptin is used for the treatment of type 2 diabetes; side effects include renal insufficiency and hypoglycemia. Saxagliptin is a competitive inhibitor of dipeptidyl peptidase 4, which reduces the rate of inactivation of enteric insulinotropic hormone and increases its concentration in the bloodstream, thereby reducing fasting and postprandial blood glucose concentrations in a glucose-dependent manner in type 2 diabetes mellitus, and is indicated for the treatment of type 2 diabetes mellitus. The drug may cause adverse reactions such as renal insufficiency, hypoglycemia, allergic reactions (e.g., urticaria and facial edema), and abnormal laboratory tests (e.g., decreased absolute lymphocyte counts). It is contraindicated in patients with a history of severe hypersensitivity reactions to the product, such as rapid-onset allergic reactions, angioedema, or exfoliative skin damage. The use of the drug should be noted that the drug can not be used in patients with type 1 diabetes or diabetic ketoacidosis; the drug should be used with caution in patients with severe renal insufficiency; if a hypersensitivity reaction occurs after the use of the drug, it should be immediately discontinued, and go to the hospital in a timely manner. If you need to use the drug patients, it is recommended to use under the guidance of a doctor, avoid unauthorized use of drugs.