TORCH: refers to pathogens that can cause congenital intrauterine infections and perinatal infections resulting in perinatal malformations. It is the abbreviation of the English name of a group of pathogenic microorganisms, of which T (Toxopasma) is Toxoplasma gondii, R (Rubella. Virus) is rubella virus, C (Cytomegalo. Virus) is cytomegalo, and H (Herpes. Virus) which is Herpes simplex type I/II. When viremia occurs in pregnant women, the virus can spread through the placenta or birth canal to infect the fetus, causing premature birth, miscarriage, stillbirth or malformation, as well as causing damage to multiple systems and organs of the newborn, resulting in various degrees of mental retardation and other symptoms. Especially in the first trimester of pregnancy, when the embryo is in the organogenesis stage, infection by virus can destroy cells or inhibit cell division and proliferation. Infection with the virus after the organ-forming stage can destroy tissues and organ structures and can lead to persistent infection. Patients with TORCH syndrome cause miscarriages and stillbirths in pregnant women, have severe intellectual disabilities after birth, and cannot take care of themselves, causing a great mental and economic burden. There are about 26,000 children born with TORCH in China every year, an average of 3 per hour, posing a great threat to eugenics and population quality, so its infection diagnosis and treatment has attracted widespread attention. After TORCH infection, patient-specific antibodies IgM and IgG can rise rapidly, with IgM appearing early and lasting 6-12 weeks, while IgG appears late but can be maintained for life. Therefore, we often consider a positive IgG as a previous infection, while a positive IgM is used as a diagnostic indicator for the first infection. If an abnormal test is found, you should seek medical attention as soon as possible.