Artificial oxalic metronidazole tablets with amoxicillin can be used to treat toothache caused by gingivitis, periodontitis or periapical inflammation, but pulpitis or apical periodontitis caused by toothache with the drug has no effect, to avoid blind use of drugs. Clinically, after the appearance of gingivitis, wisdom teeth pericoronitis, periodontitis and other diseases can be used under the guidance of a doctor to treat artificial oxalic metronidazole tablets, but also with the use of amoxicillin and other antibiotic drugs, which can alleviate the pain and eliminate the inflammation. However, if there is pulpitis, apical periodontitis and other diseases, the use of such drugs may not achieve a better effect, need to carry out root canal treatment. During the use of drugs need to follow the doctor’s instructions, but also need to pay attention to diet and oral hygiene, to avoid aggravation of the symptoms of infection.