Parkinson’s disease is a progressive disease of the nervous system that occurs in middle-aged and elderly people. The disease progresses slowly after onset, mainly manifesting as hand tremors, muscle stiffness, motor slowing and even unstable walking. Current treatment does not stop the progression of the disease, and the goal of treatment is mainly to improve symptoms and enhance the quality of life. Timely and reasonable treatment can significantly improve the working ability and quality of life of patients. 1.Levodopa is not terrible The current treatment is still mainly medication, and the most effective drug is levodopa. However, because levodopa treatment is prone to efficacy loss and some motor complications after 2-5 years, it has been misunderstood that the drug is toxic to the nervous system, which has caused “levodopa phobia” in some patients, and even if they have unstable walking and fall easily, they still worry about the side effects of levodopa and are unwilling to use or increase the dosage. As a result, some patients suffer from repeated falls and fractures, which seriously affect the quality of life of patients and even cause disability. Some clinical observations have demonstrated that before the clinical application of levodopa, patients had low quality of life and shorter life expectancy than normal people, while after the clinical application of levodopa, patients’ life expectancy was close to that of normal people, and their quality of life was significantly improved. In clinical studies, it was found that high doses of L-dopa did not cause dopaminergic neuronal damage in normal humans and normal rodents. Therefore, it can be said that levodopa is not toxic to the nervous system of patients with Parkinson’s disease. There is no need to worry too much about the side effects of levodopa. Timely levodopa treatment can reduce the risk of falls and fractures; with proper use, the occurrence of long-term complications can be reduced. Overall, the advantages of levodopa treatment far outweigh the disadvantages. 2. To pay attention to the impact of non-motor symptoms on the quality of life of Parkinson’s disease patients The impaired mobility of Parkinson’s disease has received attention from both doctors and patients and timely treatment, and non-motor symptoms are often neglected. A survey conducted by the Ministry of Health Beijing Hospital1 showed that almost all patients had non-motor symptoms, with an average of 12 non-motor symptoms per patient. For example, constipation, depressed mood, anxiety and irritability, hallucinations, sleep disturbances, cognitive impairment, urinary difficulties, and pain have a significant impact on quality of life and often make patients feel unhappy or distressed. However, patients rarely volunteer to complain about these symptoms, especially depression and anxiety, and rarely receive treatment. Other symptoms may also be misdiagnosed as other diseases and not receive reasonable and effective treatment. A comprehensive understanding of the symptoms of Parkinson’s disease is very necessary. 3. Treat Parkinson’s disease scientifically and rationally The Parkinson’s Disease and Movement Disorders Group of the Chinese Medical Association’s Neurology Branch introduced guidelines for the treatment of Parkinson’s disease in 2006 and the second edition in 2009. This guideline was developed based on a large number of scientific studies and the wisdom of Parkinson’s disease experts at home and abroad, and is a guiding document for the treatment of Parkinson’s disease. This document provides detailed opinions on the rational treatment of different stages and symptoms of Parkinson’s disease. Unfortunately, the disease is not yet curable. There are a lot of exaggerated and illegal propaganda in the society, such as “new breakthrough in Parkinson’s disease treatment”, and even using the reputation of regular hospitals to claim that they can cure Parkinson’s disease to mislead patients, so many patients believe in these propaganda and spend a lot of money to take drugs or health care products that do not have exact efficacy, which not only wastes money, but also delays the treatment. I hope the majority of patients can shine their eyes and go to a regular hospital for treatment. Beijing Hospital opened a special Parkinson’s disease clinic in the 1980s and was the first in China to establish a Parkinson’s disease treatment center in 1995. We have carried out the diagnosis and treatment of Parkinson’s disease and clinical research, hosted and participated in a number of clinical research projects at home and abroad, and accumulated a wealth of clinical experience.