1, painless lumps: lumps appearing on the breast, skin, tongue or any part of the body, without obvious painful manifestations, the lumps may be large or small, or single or multiple, with skin color as usual, without pain or itching. 2.Long-standing ulcers: ulcers on the mucous membrane or skin that do not heal for a long time. 3.Changes in moles or warts: moles or warts suddenly increase in size, deepen in color, or local itching, hair loss, roughness, ulceration, bleeding, oozing, etc. Malignant change should be suspected. 4. Nasal congestion, blood in the nose or hoarseness: unexplained nasal congestion, blood in the nose or headache in adults, and neck lumps are common symptoms of nasopharyngeal cancer. Unexplained long-term hoarseness is an early sign of laryngeal cancer. 5.Cough and blood in sputum: Unexplained cough and blood in sputum, sometimes there may be chest pain, and general anti-inflammatory treatment does not improve, so the possibility of lung cancer should be excluded. 6.Insensibility of eating: obstruction and pain when swallowing food, or feeling stuffy and uncomfortable behind the sternum, foreign body sensation in the esophagus and the tendency of gradual aggravation are common symptoms of esophageal cancer. 7.Decreased appetite, upper abdomen fullness and indigestion: usually eating well, if the above symptoms appear, you should seek medical advice in time to exclude gastrointestinal tumor. 8.Change in stool habit, blood in stool: blood and mucus in stool without clear cause (such as hemorrhoids, anal fissure, etc.), alternating diarrhea and constipation, thinning and deformation of stool, etc. are common manifestations of colorectal cancer. 9. Painless hematuria and dyspareunia: blood in urine without pain should be noted whether there is kidney or bladder tumor. Older men with difficulty and dyspareunia in urination should distinguish between prostate enlargement and prostate tumor. 10. Unexplained vaginal bleeding: irregular vaginal bleeding outside of menstruation or after menopause, contact bleeding should be examined promptly to exclude female genital tumors. 11.Unexplained prolonged weight loss.