Gout is generally not induced by proper running, but it may be induced by strenuous exercise. Gout is a joint disease caused by urate deposition in the body, and purine metabolism disorders and uric acid excretion disorders caused by hyperuricemia directly related to the etiology of the primary and secondary two. 1. Primary: Uric acid is the metabolite of purine, if the activity of ribose phosphate pyrophosphate synthetase is increased or hypoxanthine phosphoribosyltransferase is partially or completely deficient, the production of uric acid is excessive, which will lead to monosodium urate deposition, resulting in gout. 2. Secondary: alcohol consumption and consumption of high-purine food will lead to increased purine intake, is also a key factor leading to gout; such as drugs, poisoning or endogenous metabolites such as ketone bodies, lactic acid, and other factors to inhibit uric acid excretion and increased absorption can also lead to gout; myocardial infarction, acute respiratory failure can cause accelerated decomposition of ATP produces a large number of purines, causing hyperuricemia. Strenuous exercise, drinking a lot of alcohol or eating high-purine food can induce gout attacks, gout patients can be appropriate exercise, enhance the function of joint muscles, avoid drinking alcohol and high-purine diet. If diagnosed with gout, it is recommended to seek timely medical treatment to avoid the development of the disease.