Rectal mesothelioma is not necessarily a terminal disease, but a tumor with malignant potential; whether there is a possibility of cure depends on the nature and size of the mesothelioma. 1. Benign rectal mesenchymal tumor: benign rectal mesenchymal tumor is usually found in the early stage without obvious symptoms, and can be detected by anal fingerprinting. It can be resected by surgery, and use neoadjuvant chemotherapy, such as taking Gleevec can significantly shrink the tumor for easy resection, and it is not easy to recur. 2. Rectal mesenchymal tumor with potential malignancy: at this time, patients are often in the late stage of the tumor, with the possibility of metastasis, and eventually may be transferred to the liver or lungs. Therefore, in addition to surgical radical treatment, it is also necessary to cooperate with targeted therapy, and there is a possibility of cure. 3. Patients with positive surgical margins or patients who cannot be resected: the survival rate of patients in this case is not high, the median survival time is about 7 months to 2 years, and it is easy to recur after the second surgery, so the survival rate can be improved by cooperating with the doctor’s treatment. Rectal mesenchymal tumors with early detection, early treatment, there is a certain cure rate, this disease is highly specialized, should be timely to regular hospitals, under the guidance of the doctor to determine the specific treatment plan, and actively cooperate with the treatment, to avoid the deterioration of the condition.