Suctioning of sputum in infants is usually done by negative pressure suction, but it needs to be done by a professional. Infants are generally unable to expel sputum on their own, and if there is a lot of sputum, professional suction is needed. A specialized negative pressure suction device is often used in the clinic, where one end of the suction tube is placed into the child’s mouth and then operated by a healthcare professional to suction the sputum. The tube is rotated from side to side and lifted upward to facilitate the suctioning of respiratory secretions, and the suctioning time is less than 15 seconds per suction to avoid oxygen deprivation. Since the oral mucosa of infants is relatively weak, it must be operated by a doctor or professional nurse to avoid mucosal damage.