Pregnancy toothache is an oral disease that causes swelling and pain in the teeth and their adjacent organs during a woman’s pregnancy due to a variety of reasons. It often manifests as tooth pain, swelling of the face, pain that can be aggravated at night with a burning sensation, and difficulty in opening the mouth that affects eating. The common causes are as follows: the consumption of overly greasy, dry and spicy food during pregnancy, which leads to maternal fire, resulting in toothache; it may be due to the change in the diet structure of pregnant women during pregnancy, preferring sweet and sour food, the increase in the number of meals, and the neglect of oral hygiene resulting in the proliferation of tooth decay, resulting in toothache; it may be due to the influence of progesterone, the upward adjustment of hormone levels during pregnancy It may be caused by the upward adjustment of hormone level during pregnancy, which causes the expansion of gum capillaries, resulting in swelling and bleeding of gums, inflammation of gums and wisdom teeth, etc.; and it may also be caused by tumors in the gums that stimulate the gums and cause pain. Since drugs may adversely affect the fetus during pregnancy, resulting in many drugs cannot be used, if the symptoms are more serious should promptly go to the hospital, the doctor can give the appropriate physical therapy according to the cause of the disease and the condition of the disease, to minimize the damage. Finally, pre-pregnancy medical examination, especially oral disease examination, is the basis for preventing toothache in pregnancy, and paying attention to oral hygiene during pregnancy is the key.