In patients with vague pain on the right side of the lower ribs, it is most often associated with diseases of the liver and gallbladder. Because the right side of the lower ribs is mainly the liver and gallbladder, after this situation, liver diseases such as hepatitis, liver cysts, liver tumors and cholecystitis, gallbladder stones, gallbladder polyps or tumors in the gallbladder area should be considered, which can lead to vague pain on the right side of the lower ribs. Therefore, after the occurrence of this condition, liver and biliary ultrasound examination should be performed, while blood sampling to check liver function, mainly to observe the causes of the vague pain under the right side of the rib cage, to identify the cause and then treat the cause, the effect is more desirable, to avoid blind treatment delay the disease, affecting the patient’s life.